Retatrutide

Axova Research Retatrutide is a high-purity, synthetic 39-amino-acid peptide designed as a single-sequence triple agonist. In biological, metabolic, and endocrinology research models, Retatrutide is extensively studied for its simultaneous structural co-agonism across three critical inkretin and metabolic receptor systems: the gastric inhibitory polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon receptor (GCGR).

The specific architecture of this molecule is a primary subject of investigative interest for studying multi-pathway nutrient-sensing mechanics. Researchers utilize this compound to analyze the compound’s impact on energy balance, glucose-dependent insulin secretion pathways, and upregulated lipolytic gene expression independent of traditional single-agonist constraints.

Investigative Highlights:

• Triple Agonist Signaling: Researching the simultaneous activation of GIP, GLP-1, and Glucagon receptors to observe synergistic cellular responses.
• Adipose Tissue Energetics: Investigating glucagon receptor recruitment mechanisms to study direct energy expenditure and metabolic rate adaptation in laboratory models.
• Endocrine Loop Stabilities: Studying systemic homeostasis, appetite-regulation neurochemistry, and glycemic curves within complex metabolic profiles.

Technical Specifications:

• Chemical Profile: GIP/GLP-1/GCGR Triple Receptor Agonist
• Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
• Molecular Weight: 4731.33 g/mol
• CAS Number: 2381089-83-2
• Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys-Aib-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
• Purity: 99%+ (Verified by HPLC/MS)
• Physical State: Lyophilized white powder

Storage & Handling:

• Storage: Store desiccated at -20°C for optimal long-term stability. Post-reconstitution, store refrigerated at 2-8°C.
• Reconstitution: For precise analytical measurements and maximum peptide integrity, utilize Axova Research Bacteriostatic Water.

Shipping & Logistics:

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Research Disclaimer:

• This product is strictly for Laboratory Research Use Only. Not for human or veterinary administration.