Epithalon

Axova Research Epithalon (also recognized as Epitalon or Epithalone) is a high-purity synthetic tetrapeptide based on epithalamin, a natural peptide extract produced in the pineal gland. In molecular and cellular longevity models, Epithalon is a primary subject of interest for its potential to interact directly with DNA structures, specifically investigated for its role in upregulating telomerase activity.

By stimulating the telomerase enzyme, this short-chain bioregulator is studied for its capacity to assist in elongation or structural maintenance of telomeres, allowing researchers to observe cellular replication limits and senescence pathways. Additionally, its interactions with pineal pathways make it a frequent component in studies analyzing melatonin production and the restoration of disrupted circadian rhythms.

Investigative Highlights:

• Telomerase Activation: Researching the mechanical upregulation of telomerase to study cellular life cycles and replication limits.
• Pineal Pathway Signaling: Investigating the normalization of endogenous melatonin synthesis and systemic neuroendocrine regulation.
• High Structural Stability: Utilizing its ultra-short, four-amino-acid chain to study peptide resistance against rapid enzymatic breakdown post-reconstitution.

Technical Specifications:

• Chemical Profile: Pineal-Gland Derived Peptide Bioregulator
• Molecular Formula: C₁₄H₂₂N₄O₉
• Molecular Weight: 390.35 g/mol
• CAS Number: 307297-39-8
• Sequence: H-Ala-Glu-Asp-Gly-OH
• Purity: 99%+ (Verified by HPLC/MS)
• Physical State: Lyophilized white powder

Storage & Handling:

• Storage: Store desiccated at -20°C for optimal long-term stability. Post-reconstitution, store refrigerated at 2-8°C.
• Reconstitution: For precise analytical measurements and maximum peptide integrity, utilize Axova Research Bacteriostatic Water.

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Research Disclaimer:

• This product is strictly for Laboratory Research Use Only. Not for human or veterinary administration.