Tesamorelin

Axova Research Tesamorelin is a high-purity synthetic peptide featuring a modified N-terminus (trans-3-hexenoic acid) designed to significantly enhance structural stability against enzymatic degradation compared to endogenous GHRH. In biological and metabolic research models, Tesamorelin is widely investigated for its unique capacity to bind and activate pituitary GHRH receptors, stimulating the pulsatile synthesis and secretion of growth hormone.

Because it operates natively within existing biological regulatory systems, it is a primary subject for studies analyzing lipolytic pathways, systemic insulin-like growth factor (IGF-1) modulation, and the targeted reduction of deep visceral adipose tissue without disrupting normal homeostatic feedback mechanisms.

Investigative Highlights:

• Pituitary Receptor Binding: Researching the targeted activation of GHRH receptors to study biological growth hormone release cascades.
• Visceral Adipose Lipolysis: Investigating cellular signaling mechanisms that selectively trigger fat breakdown in deep abdominal tissue.
• Enzymatic Resistance: Studying the structural impact of N-terminal modification on prolonged peptide survival and structural half-life.

Technical Specifications:

• Chemical Profile: Stabilized Growth Hormone-Releasing Hormone (GHRH) Analog
• Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S
• Molecular Weight: 5135.89 g/mol
• CAS Number: 218949-48-5
• Sequence: trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
• Purity: 99%+ (Verified by HPLC/MS)
• Physical State: Lyophilized white powder

Storage & Handling:

• Storage: Store desiccated at -20°C for optimal long-term stability. Post-reconstitution, store refrigerated at 2-8°C.
• Reconstitution: For precise analytical measurements and maximum peptide integrity, utilize Axova Research Bacteriostatic Water.

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Research Disclaimer:

• This product is strictly for Laboratory Research Use Only. Not for human or veterinary administration.