A copper-complexed tripeptide (Glycyl-L-histidyl-L-lysine copper) widely investigated for its regulatory influence on gene expression, extracellular matrix (ECM) remodeling, and cellular regeneration signaling.
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Axova Research Epithalon (also recognized as Epitalon or Epithalone) is a high-purity synthetic tetrapeptide based on epithalamin, a natural peptide extract produced in the pineal gland. In molecular and cellular longevity models, Epithalon is a primary subject of interest for its potential to interact directly with DNA structures, specifically investigated for its role in upregulating telomerase activity.

By stimulating the telomerase enzyme, this short-chain bioregulator is studied for its capacity to assist in elongation or structural maintenance of telomeres, allowing researchers to observe cellular replication limits and senescence pathways. Additionally, its interactions with pineal pathways make it a frequent component in studies analyzing melatonin production and the restoration of disrupted circadian rhythms.

Investigative Highlights

Extracellular Matrix OptimizationResearching the acceleration of collagen, elastin, and glycosaminoglycan synthesis in tissue models.
Gene Expression Modulation Studying the peptide's ability to revert aging or damaged cellular structures to a more youthful, regenerative state.
Distinct Visual IdentificationUtilizing its deep blue structural hue to verify optimal, stable copper-to-peptide stoichiometric complexing.
Chemical ProfileGlycyl-L-Histidyl-L-Lysine Copper Complex
Molecular FormulaC14H24N6O4
Molecular Weight 401.91 g/mol
CAS Number 49557-75-7
SequenceH-Gly-His-Lys-OH · Cu2+
Purity 99%+
Physical StateLyophilized deep blue powder
Storage Store desiccated at -20°C for optimal long-term stability. Protect from prolonged light exposure.
ReconstitutionFor precise analytical measurements and maximum peptide integrity, utilize Axova Research Bacteriostatic Water.
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This product is strictly for Laboratory Research Use Only. Not for human or veterinary administration.

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