Axova Research MOTS-c is a high-purity laboratory reagent representing the unique mitochondrial open reading frame of the 12S rRNA type-c peptide. In biological and metabolic research models, MOTS-c is extensively investigated for its cellular autonomous signaling mechanisms that directly target metabolic homeostasis.
Unlike nuclear-encoded hormones, MOTS-c acts as an intracellular metabolic regulator. It is heavily utilized in laboratory studies to observe the activation of the AMP-activated protein kinase (AMPK) pathway, the upregulation of glucose transporter expressions (such as GLUT4), and the potential systemic reversals of diet-induced insulin resistance models.
| AMPK Pathway Activation | Researching cellular survival mechanisms, energy sensing, and nutrient-deprivation signaling cascades. |
| Exercise-Mimetic Profiling | Investigating skeletal muscle glucose uptake and physical performance indicators in cellular models. |
| Mitochondrial Homeostasis | Studying the cross-talk between mitochondrial and nuclear genomes during systemic metabolic stress. |
| Chemical Profile | Mitochondria-derived open reading frame of 12S rRNA peptide-c |
| Molecular Formula | C101H152N28O22S2 |
| Molecular Weight | 2174.62 g/mol |
| CAS Number | 1627503-51-9 |
| Sequence | H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Leu-Pro-Arg-Lys-Leu-Arg-NH2 |
| Purity | 99%+ |
| Physical State | Lyophilized white powder |
| Storage | Store desiccated at -20°C for optimal long-term stability. Note: Due to the sensitive structural nature of mitochondrial peptides, keep away from structural moisture. |
| Reconstitution | For precise analytical measurements and maximum peptide integrity, utilize Axova Research Bacteriostatic Water. |
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This product is strictly for Laboratory Research Use Only. Not for human or veterinary administration.
Axova Research supplies reference peptides to verified laboratories for research purposes only. Because you did not confirm you are 21 years of age or older and agree to our terms, access is not permitted.
